ABSTRACT
Iran has a population of ~83 million people with marked cultural and economic differences. Due to culture and consanguineous marriage, inherited neuromuscular diseases (NMDs) are more common than some other countries. Iranian registry of SMA patients has been started with the onset of the outbreak of Covid-19. Due to the multi-organ involvement in COVID-19 infection and higher risks of mortality and morbidity for the neuromuscular disorders, ofering rehabilitation and management of these patients especially SMA can be highly effective in the complications of the disease as well as the number of hospitalizations. With considering this situation, new platform for registry and management of SMA has been developed. In this platform, Tele rehabilitation as well as the creation of parent organizations, are contributing to the increased quality of the management of SMA patients. Over the past months, this care has provided new experiments. This article describes the outcome of this joint efort and shares the experience gained in this registry.
ABSTRACT
Serious, and sometimes, deadly complications of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are devastating. Whereas most manifestations of COVID-19 are respiratory (fever, dry cough, fatigue, pneumonia), it is getting to be progressively recognized that numerous organ functions can be affected by this disease, and the nervous system is one of them as neurological complications can affect up to 36% of adult patients. However, the prevalence and pathophysiology of these complications have yet to be fully elucidated in children. Here, we discuss an infant with neurological symptoms manifested as chronic isolated aseptic meningitis associated with COVID-19, which was unresponsive to ordinary treatments and dramatically responsive to dexamethasone. Immune-mediated reactions may have had a major pathophysiologic role in this case. © 2021, Author(s).